Xu Yu, MD

Lab Info:

Principal Investigator:
Xu Yu, MD

Lab Staff:
4 post docs
1 bioinformatician
1 PhD student
4 technicians
1 undergraduate researcher
Openings: postdoctoral fellow (https://www.nature.com/naturecareers/job/postdoctoral-fellow-positions-at-mghbwhhms-massachusetts-general-hospital-702219)
Research Technician (https://app.joinhandshake.com/jobs/2985698?ref=preview-header-click)

Office/Location: 400TS RM758

Phone: (857) 268-7004

Email: xyu@partners.org

Category: Core Members, Ragon Members

Dr. Xu Yu is an Associate Professor of Medicine at Harvard Medical School, a Physician Investigator at Massachusetts General Hospital and an Associate Immunologist at Brigham and Women’s Hospital. She is also an Affiliated Member of the Broad Institute and a Group Leader at the Ragon Institute of MGH, MIT and Harvard.


Dr. Yu brings a clinical lens to investigating the molecular and cellular mechanisms involved in immune control of HIV-1. One area of investigation includes the role of dendritic cells and their immunoregulatory functions for generating and fine-tuning adaptive immune responses during HIV-1 infection. These studies focus on how innate immune recognition pathways that sense HIV-1 RNA or DNA in dendritic cells contribute to HIV immune control. In addition, the Yu lab centers on the analysis of immunological networks associated with immune control of HIV-1 and Zika virus using systems biology–based approaches. These studies use large-scale, unbiased techniques for generating global pictures of immune defense mechanisms against HIV-1 and Zika virus by combining high-throughput genomics, proteomics, and transcriptomics technologies with functional immunologic and virologic assays. These two research areas are approached in an interdisciplinary fashion through strategic collaborations with computational biologists, chemical and material scientists, infectious disease physicians, and molecular biologists and are designed to contribute to clinical strategies that may increase host resistance against HIV-1. Dr. Yu combines her work as a basic science immunologist with clinical and translational perspectives for improving clinical treatment options for viral infectious disease. For instance, she is actively involved in clinical trials in HIV-1-infected patients and serves as the protocol immunologist for ACTG study 5308 (antiretroviral treatment of HIV-1 controllers) and for three NIH U01-funded pilot clinical trials.


Dr. Yu is an elected member of the American Society for Clinical Investigator (ASCI), the recipient of the Claflin Distinguished Scholar Award and the Stephen Krane Excellence in Research Award from MGH and the Clinical Scientist Development Award from the Doris Duke Charitable Foundation. She received an MD from China Medical University in Shenyang, China, and completed postdoctoral training in the AIDS Research Center at MGH.





  • Runner-up Science 2020 Breakthrough of the Year — Science Magazine
  • A Woman May Have Been Cured of H.I.V. Without Medical Treatment — New York Times
  • How Elite Controllers Tame HIV without Drugs — Science Magazine
  • A Rare Group of HIV Patients — Newsweek
  • Dendritic cells of elite controllers able to recognize, mount defense against HIV — MGH News
  • The role of dendritic cells in keeping HIV in check without drugs — Eurek Alert (AAAS)
  • Some people can resist the ravages of HIV – here’s how — New Scientist
  • Dendritic cells may hold key to elite controllers’ immune response — Healio
  • Dendritic cells of elite controllers able to recognize, mount defense against HIV — Medical Xpress



Major Recent Publications

1. Jiang C, Lian L, Gao C, Sun X, Einkauf K, Chevalier JM, Chen S, Hua S, Rhee B, Chang K, Blackmer JE, Osborn M, Peluso MJ, Hoh R, Somsouk M, Milush J, Bertagnolli LN, Sweet S, Varriale J, Burbelo PD, Chun TW, Laird GM, Serrao E, Engelman AN, Carrington M, Siliciano RF, Siliciano J, Deeks SG, Walker BD, Lichterfeld M, Yu XG. Distinct viral reservoirs in individuals with spontaneous control of HIV-1. Nature 2020. Aug 26. doi: 10.1038/s41586-020-2651-8.


2. Sun X, Hua S, Gao C, Blackmer J, Ouyang Z, Ard K, Ciaranello A, Yawetz S, Sax PE, Rosenberg ES, Lichterfeld M, Yu XG*. Immune-profiling of ZIKV-infected patients identifies a distinct function of plasmacytoid dendritic cells for immune cross-regulation. Nat Comms. 2020. May 15;11(1):2421. doi: 10.1038/s41467-020-16217-5.


3. Martin-Gayo E, Gao Ce, Chen XR, Ouyang Z, Kim D, Kolb KE, Shalek AK, Walker BD, Lichterfeld M, Yu XG*. Immunological fingerprints of controllers developing neutralizing HIV-1 antibodies. Cell Reports. 2020. Jan 28;30(4):984-996.e4.


4. Chowdhury FZ, Ouyang Z, Buzon M, Walker BD, Lichterfeld M, Yu XG. Metabolic pathway activation distinguishes transcriptional signatures of CD8 T cells from HIV-1 elite controllers. AIDS, 2018. Nov 28;32(18):2669-2677.


5. Hua S, Vigano S, Tse S, Harrington S, Negron J, Garcia-Broncano P, Resino S, Leal M, Ruiz-Mateos E, Lichterfeld M, Yu XG. Pegylated IFN-α induces NK cell-dependent HIV-1 DNA decline in ART-treated HIV-1/HCV co-infected patients. Clin Infect Dis. 2018 Jun 1;66(12):1910-1917.


6. Martin-Gayo E, Cole MB, Kolb KE, Ouyang Z, Cronin J, Kazer SW, Ordovas-Montanes J, Lichterfeld M, Walker BD, Yosef N, Shalek AK, Yu XG. A Reproducibility-Based Computational Framework Identifies An Inducible Enhanced Antiviral Dendritic Cell State In HIV-1 Elite Controllers. Genome Biology. 2018 Jan 29;19(1):10.


7. Sun X, Hua S, Chen HR, Ouyang Z, Einkauf K, Tse S, Ard K, Ciaranello A, Yawetz S, Sax P, Rosenberg ES, Lichterfeld M, Yu XG. Host factors enabling ZIKA virus replication in dendritic cells from individuals with Zika virus infection. Cell Rep. 2017 Dec 19;21(12):3471-3482.


8. Martin-Gayo E, Cronin J, Hickman T, Ouyang Z, Lindqvist M, Kolb KE, Schulze zur Wiesch J, Cubas R, Porichis F, Shalek A, van Lunzen J, Haddad E, Walker BD, Kaufmann D, Lichterfeld M, Yu XG. Circulating CXCR5+CXCR3+PD-1Lo Tfh-like cells in HIV-1 controllers with neutralizing antibody. JCI Insight.2017; 2(2):e89574.


9. Viganò S, Negrón JJ, Tse S, Chowdhury FZ,Lichterfeld M, Yu XG. HLA-G+ HIV-1-specific CD8 T cells are associated with HIV-1 immune control. AIDS. 2017; 31(2):207-212.


7. Gayo E, Buzon M, Ouyang Z, Hickman T, Cronin J, Pimenova D, Walker BD, Lichterfeld M, Yu XG. Potent cell-intrinsic immune responses in dendritic cells facilitate HIV-1-specific T cell immunity in HIV-1 Elite Controllers. PLoS Pathogens. June 11, 2015. DOI:10.1371/journal.ppat.1004930.


9. Bashirova A, Martin-Gayo E, Jones DC, Qi Y, Apps R, Gao X, Burke PS, Taylor CJ, Rogich J, Wolinsky S, Bream JH, Duggal P, Hussain S, Martinson J, Weintrob A, Kirk GD, Fellay J, Buchbinder SP, Goedert JJ, Deeks SG, Pereyra F, Trowsdale J, Lichterfeld M, Telenti A, Walker BD, Allen RL, Carrington M, Yu XG. LILRB2 interaction with HLA class I correlates with control of HIV-1 infection. PLOS Genetics. 2014. Mar 6;10(3):e1004196. PMID: 24603468.

More Publications

Current Members


Xiaoming Sun | xsun16@mgh.harvard.edu

Xiaoming joined Dr. Yu’s group as a Research Fellow in July 2015. He received his PhD in Immunology in 2014 at Kumamoto University, under the mentorship of Dr. Masafumi Takiguchi, where he studied HIV-1 escape mutations and CD8 Cytotoxic T lymphocytes. After his PhD studies, he moved to Boston to join Dr. Yu’s group where he studies immune response to ZIKA virus, as well as HIV-1 immune defense in Elite Controllers using a system immunology approach. When not in lab, he serves as vice-president of the Massachusetts General Hospital Chinese Scientists and Staff Association (MGH-CSSA). Additionally, he enjoys photography, reading, and spending time with his family and friends.


Kevin Einkauf | keinkauf@partners.org

Kevin joined Dr. Yu’s and Dr. Lichterfeld’s labs as a Research Technician in June 2016 after receiving his B.A. in Neurobiology from Harvard College. In his undergraduate research, Kevin worked at McLean Hospital, studying the neural circuitry underlying depression and substance abuse. He also spent time as a research fellow at the Botswana-Harvard AIDS Institute Partnership in Gaborone, Botswana, studying HIV-1 drug resistance. Currently, Kevin is primarily focused on understanding the latent HIV-1 reservoir and how it responds to various clinical interventions. In his free time, Kevin enjoys hiking, traveling, and eating hot pot.


Ce (Charlie) Gao  | cgao4@mgh.harvard.edu

Ce (Charlie) joined Dr. Yu’s and Dr. Lichterfeld’s labs in July 2017 as a Bioinformatics Specialist. He received his PhD in Bioengineering from Northeastern University and worked as a Postdoctoral Fellow at Beth Israel Deaconess Medical Center/Harvard Medical School, where he worked on cancer immunotherapy projects. He is currently collaborating with researchers in the lab on various projects related to HIV and ZIKA, including analyses regarding genomics, transcriptomics, and proteomics. In addition, he is responsible for the computational infrastructure of the lab. Outside the lab, he enjoys running, swimming, reading/listening to books, and watching movies.


Xiaodong Lian  | xlian1@mgh.harvard.edu

Xiaodong joined Dr. Yu’s and Dr. Lichterfeld’s labs in September 2017 as a visiting PhD student. He is a graduate student from the Kunming Institute of Zoology, Chinese Academy of Sciences, where he studied MHC/HLA splicing variants and pig-tailed macaque animal models of HIV/AIDS. He currently works on understanding the viral reservoir in HIV controllers using viral genome sequencing. In his free time, Xiaodong enjoys watching movies, playing video games, hiking, and traveling with his friends.


Ciputra (Adi) Hartana | chartana@mgh.harvard.edu

Ciputra joined Dr. Yu’s lab in October 2018 as a Postdoctoral Research Fellow. After finishing medical school in Indonesia, he joined Ola Winqvist’s lab at Karolinska Institutet, Sweden as a PhD student, where he received his PhD in immunology in September 2018, in which he investigated the immunomodulation of CD8 T cells, CD4 T cells and regulatory T cells in the solid tumor microenvironment of cancer patients. His current work explores the role of long noncoding RNA on dendritic cells from elite controller HIV patients. In his spare time, Ciputra likes to listen to jazz music and mix cocktail drinks.


Ben Rhee | brhee1@mgh.harvard.edu

Ben joined Dr. Yu’s lab in June 2018 as an undergraduate researcher. He is currently attending Harvard University, where he is concentrating in Integrative Biology. In the lab, he works on mapping the viral reservoir in HIV controllers using viral genome sequencing. In his free time, Ben enjoys swimming, playing violin, watching horror movies with his friends, and playing poker.


Kyra Seiger | kwseiger@mgh.harvard.edu

Kyra joined Dr. Yu’s and Dr. Lichterfeld’s labs as a Research Technician in June 2019 after receiving her B.A. in Biology from Mount Holyoke College. During her undergraduate research, Kyra worked on a pre-clinical Chlamydia trachomatis vaccine trial and studied in vivo virulence factor gene expression during C. trachomatisinfection. She is currently interested in better understanding the latent HIV-1 reservoirs in HAART patients. Outside of lab, Kyra spends her time hiking, reading, chatting with friends, and trying every bakery in the Boston area.


Matt Osborn | mosborn1@mgh.harvard.edu

Matt joined Dr. Yu’s and Dr. Lichterfeld’s labs as a Research Technician in July 2019 after receiving his B.A. in Biochemistry and Physics and M.S. in Chemistry from the University of Pennsylvania. In his undergraduate research, he developed organs-on-chips to model heterogeneous tissues in human diseases. Matt is mainly working on sequencing and understanding the latent HIV-1 reservoir in patients undergoing ART. In his free time, he enjoys cooking, playing guitar, staying active, and trying to find quality cheap eats in Boston.


Yelizaveta (Liza) Rassadkinayrassadkina@mgh.harvard.edu

Liza joined Dr. Yu’s lab as a Research Technician in July 2019 after graduating from Rutgers University. At Rutgers, she received her B.S. in Microbiology.  She did research on the microbial communities of Yellowstone National Park while focusing on bacterial and archaeal growth in mercury enriched hot springs to look for mercury resistance and mercury methylation. Currently, she is interested in immunology and virology while working on clinical trials that involve adult and infant patients that are HIV-1 reservoirs. Outside of lab, Liza spends her time reading, swimming, going to museums and aquariums, and watching documentaries.


Weiwei Sun | wwsun@mgh.harvard.edu

Weiwei joined Dr. Yu’s and Dr. Lichterfeld’s labs as a Postdoctoral Research Fellow in September 2019. She received her PhD in Microbiology in 2017 and then worked as a Research Assistant for another two years at Institut Pasteur of Shanghai, Chinese Academy of Sciences, where she studied HIV and host interaction and the molecular mechanism of latent infection. She currently works on understanding the viral reservoir in HAART treated patients. In her free time, Weiwei enjoys watching movies, exploring Boston, and traveling with her friends.


Catherine Koofhethile | ckoofhethile@mgh.harvard.edu

Originally from Botswana, Dr. Catherine Koofhethile is a Postdoctoral fellow who recently joined Dr. Xu Yu and Dr. Mathias Lichterfeld’s lab in September 2019. She received her BSc in Medical Microbiology from the University of Surrey (UK) with the generosity of the Government of Botswana’s Ministry of Education Scholarship, and later completed a Masters’ degree in Immunology from the University of Birmingham (UK) as a self-sponsored student. Following her MSc, she spent a couple of years as a Graduate Research assistant at Oxford University (Goulder lab) where she was part of the team that characterized HIV specific immune responses in both B and C clade infected individuals. She completed her PhD in Immunology in 2016 at the HIV Pathogenesis Program (HPP), University of KwaZulu-Natal, South Africa with the generosity of the PhD scholarship she received from The Organization for Women in Science for the Developing World (OWSD). Her PhD project aimed to understand the factors that mediate virologic control and lack of control in individuals with HIV-1C infection in the absence of antiretroviral therapy (ART). She later joined the Essex lab at Harvard T. H. Chan School of Public Health (HSPH) as a postdoctoral/Fogarty fellow in 2017. She is currently working on a research project that is assessing the reservoir in HIV-1C infected adolescents from Botswana receiving long-term ART (>10 years). Catherine also holds a Research Associate position at Botswana Harvard AIDS Institute Partnership (BHP). Outside of work, Catherine is a Sunday School teacher, enjoys singing, traveling and is generally a lover of life.


Former Members

Jane Blackmer  | jeblackmer@mgh.harvard.edu

Jane joined Dr. Yu’s and Dr. Lichterfeld’s labs in June 2018 as a Research Technician after graduating from Tufts University. At Tufts, she received her B.S. in Biology while studying trinucleotide repeat instability and DNA double-strand break repair in Drosophila. Currently, she is interested in doing molecular virology work to understand the latent HIV-1 reservoir. Outside of lab, Jane enjoys music, reading, and spending time with friends and family.


Joshua Chevalier | jmchevalier@mgh.harvard.edu

Joshua joined Dr. Yu’s and Dr. Lichterfeld’s labs as a Research Technician in June 2018. He graduated from the University of Massachusetts Amherst with a B.S. in Biology, where he researched the replicative polymerases of the parasite Trypanosoma brucei. He has always been interested in studying infectious disease and will be analyzing the latent HIV-1 reservoir in HAART treated patients.  Outside of lab, Joshua enjoys exploring nature, traveling to new places, and spending time with friends.


Chenyang Jiang  | cjiang5@mgh.harvard.edu

Chenyang joined Dr. Yu’s and Dr. Lichterfeld’s labs as a Research Technician II and Lab Manager in August 2017 after graduating from the University of Connecticut with MS in Pathobiology. She received her BS in Biological Sciences in 2016 from Sichuan University in China. Previously, Chenyang focused her research on house dust mite-induced allergic airway disease in murine models of sickle cell disease. She switched from Pathobiology to Virology and Immunology work, and is now investigating possible alterations of HIV-1 viruses in HIV elite controllers and viremic controllers by doing full genome sequencing. In her free time, she enjoys traveling, reading, watching movies, and exploring Boston cuisine with friends.


Pilar Garcia Broncano | pgarciabroncano@mgh.harvard.edu

Pilar received her PhD in 2017 at the Complutense University of Madrid, where she studied immune cell dysfunction and hyperactivation in HIV/HCV coinfected patients, as well as the in vitro and in vivo activity of nanoparticles against HIV-1 and HSV-2 infections to prevent their transmission in humans as a topical microbicide. She joined Dr. Yu’s and Dr. Lichterfeld’s labs in January 2016 as a visiting PhD student to study possible alterations in the HIV reservoir due to HCV treatment using HIV full genome sequencing in HIV/HCV coinfected patients. She returned to the lab in October 2016, as a Graduate Research Assistant while completing her PhD studies. She is currently a Research Fellow who is studying the immunological and virological characterization of HIV-1-infected patients who are taking antiretroviral therapy and various viral reactivation agents in several ongoing clinical trials. Pilar enjoys scuba diving, snowboarding, running and traveling in her free time.



Fatema (Navin) Chowdhury | fchowdhury@partners.org

Navin joined Dr. Yu’s and Dr. Lichterfeld’s groups in August of 2014 as a Research Fellow. She received her PhD in Immunology at UT Southwestern Medical Center, where she studied how innate cytokines regulate CD8+ T cell function. She is interested in infectious diseases in the context of global health and will study immune response to HIV-1. A native of Bangladesh, Navin grew up in the beautiful tea gardens of Srimongol and developed a love for the wilderness. She loves to travel around the world in search of culture and cuisine.


Shivaali Maddali  | smaddali@mgh.harvard.edu

Shivaali joined Dr. Yu’s and Dr. Lichterfeld’s labs in June 2017 as a Research Technician, Lab Manager, and Clinical Research Coordinator. She received her BS in Biomedical Engineering from Brown University, where she used 3D printing methods to develop biomimetic in vitro platforms to study cancer metastasis. Her current work utilizes flow cytometry to study peptide recognition in the context of the HIV-1 immune response. When not in the lab, Shivaali enjoys traveling, photography, watching football, playing soccer, and spending time with friends and family.


Stephane Hua | shua4@mgh.harvard.edu

Stephane joined Dr. Yu’s group in September 2015 as a Research Fellow. He received his PhD in immunology at INSERM U1012 in France under the supervision of Dr. Alain Venet and has characterized different subsets of HIV-specific CD8+ T cells in HIV infected patients. He is now investigating the effect of type I interferon in the immune response in HCV/HIV coinfected patients and in HIV infected patients. When not at work, he enjoys visiting new places, watching and playing sports (football, badminton) and watching movies.


Samantha Chen | samantha.chen@mgh.harvard.edu

Samantha joined Dr. Yu’s lab in May 2017 as a Research Fellow. She received her PhD in Microbiology and Immunology from the AIDS Institute at the University of Hong Kong, where she studied HIV-specific immune responses after PD1-based DNA vaccination in murine and rhesus macaque models. She is now investigating adaptive and innate immunity of HIV elite controllers, viremic controllers and HIV-treated patients. When not in lab, Samantha enjoys seeing live music, rock climbing, exploring nature, and traveling around the world.



Enrique Gayo | egayo@partners.org

Enrique obtained his PhD in Molecular Biology and Immunology in 2010 at the Universidad Autonoma de Madrid, under the supervision of Dr. Maria Luisa Toribio, where he studied the developmental origin of intrathymic dendritic cells and their contribution in the generation of natural T regulatory cells. After his PhD studies, he moved to Boston to join Dr. Yu’s group where he is currently studying the involvement of dendritic cell function in the spontaneous control of HIV-1 infection. In the past 5 years as a postdoctoral investigator, Enrique has produced 3 first authored publications and a bibliographical review. Additionally, he has been awarded two developmental awards from the Harvard University CFAR and the Massachusetts General Hospital ECOR programs. Enrique is a very social person who loves sports and every form of art, especially painting. He also enjoys hiking and everything related to nature and outdoor activities.


Naira Aleksanyan | naleksanyan@partners.org

Naira joined the Dr. Yu and Dr. Lichterfeld’s lab in 2016 as a research technician and clinical research coordinator. She received her BS in Biology from Suffolk University in Boston. In the past, Naira has investigated bacterial mating of Bacillus subtilis and Clostridium difficile attachment to intestinal cells. She is excited to switch from bacterial to viral work, and is currently learning to minimize killing PBMCs and infecting them with HIV. In her free time, Naira enjoys swimming, hiking, traveling, learning new idioms, and playing with goats.


Zhengyu Ouyang | zouyang@partners.org

Zhengyu Ouyang joined Yu’s group as bioinformatics specialist in June 2012. He prefers to be called “O’Young”. He received his Bachelor’s degree in telecommunication engineering and Master’s degree on pattern recognitions from Beijing University of Posts and Telecommunications (P.R. China). Ouyang earned his PhD in Computer Science (bioinformatics) from New Mexico State University in 2012. He focuses on computational and statistical analysis of molecular biological high-throughput genetic data to support biologists to test their hypotheses. Ouyang used to be a sprinter and still enjoys running, hiking and swimming, as well as other outdoor sports. Travelling and camping are definitely ranked on the top of his favorites.



William McNeil | wmcneil@partners.org

Will received his BS in Biology and Community Health from Tufts University, where he studied chitin deacetylase enzymes as potential drug targets against lymphatic filariasis.  He joined Dr. Yu’s lab in the spring of 2015 as a research technician studying the virology and immunology of the HIV-1 reservoir, as well as the role toll-like receptors play in regards to HIV infection and integration into host cell chromosomes. Will enjoys spending time outdoors running, hiking, and participating in adrenaline-filled activities such as windsurfing and skydiving. He also likes traveling and learning to cook dishes from around the world.



Samantha Tse | stse1@partners.org

Samantha is originally from Boston and received her BS in Biology at Boston College in the spring of 2014. She joined the Dr. Yu’s and Dr. Lichterfeld’s Labs shortly after in the summer of 2014 and is currently working as a Research Technician at the Ragon Institute with Dr. Dhohyung Kim studying systems biology in regards to elite controllers. When not in lab, she enjoys participating in adrenaline-inducing activities, such as rollercoasters, ziplining, and go-kart racing. She also enjoys hip hop dancing, karaoking, and hiking on long trails. Sammy is currently enrolled in a PhD/MD program at University of Massachusetts Medical School. She is interested in studying gut microbiome effects on the immune system.


Sean Harrington

Sean Harrington | sharrington7@partners.org

Sean received his BS in Biochemistry from Northeastern University in December 2013. He joined Dr. Yu’s and Dr. Lichterfeld’s labs as a research technician and a lab manager in the spring of 2014, working to further understand the HIV-1 reservoir. When not in the lab, he enjoys going on runs around Boston and baking. Sean currently conducts cancer research at Bluebird Bio in Cambridge.



Jacquie Cronin

Jacquie Cronin | jcronin7@partners.org

Jacquie received her BS in Biology from Saint Michael’s College in Vermont in 2013. The following summer she worked as a research technician at the University of Vermont, where she studied protein kinase A expression and interaction with other tyrosine kinases. Jacquie joined the Yu lab during the spring of 2014. She is currently a research technician studying the role of dendritic cells in HIV infection. When not in the lab, Jacquie loves spending time at the beach, anything fitness related, and teaching children how to ice skate. She is now conducting research on MERS-CoV in a government funded lab and enjoying the slopes and mountains in Montana.


Dhohyung‎ Kim

Dhohyung Kim | dkim26@partners.org

Dhohyung Kim is a Research Fellow at the Ragon Institute. He received his PhD in Molecular, Cellular and Developmental Biology under the mentorship of Dr. Stefan Niewiesk, at the Ohio State University. In the Dr. Yu’s and Dr. Lichterfeld’s Labs, Dhohyung studies the host cyclin-dependent kinases and HIV-1 reverse transcription, as well as the T cell intrinsic responses in various patient cohorts to HIV-1 infections. When not at work he enjoys traveling and driving around the city.



Jordi Negron | jnegron@partners.org

Jordi joined Dr. Xu Yu’s Lab in the summer of 2013 as a Research Technician and Lab Manager after graduating from Brown University with an ScB in Chemical Biology. He studies the role of CD8 T cell subsets in HIV infection through flow cytometry analysis. Outside of the lab, Jordi likes learning about other cultures and languages; this leads him to take trips around town looking for new areas to explore or to ask people at the Ragon what it is like living in different countries.



Taylor Hickman

Taylor graduated from the University of New Hampshire with a BS in Biochemistry in 2012. She joined the Xu Yu lab in the summer of 2012 as a research technician studying the role of dendritic cells in HIV infection, and as a Yu lab manager. In her spare time, Taylor enjoys running and listening to country music. Taylor left the Xu lab in June 2014 to do Oncology research at Novartis.



Patrick Burke

Patrick is from outside of New Haven, CT and graduated from Boston College with a BS in Biology and a minor in Computer Science. After graduation, he spent two years working as a technician under the tutelage of Dr. Xu Yu at the Ragon Institute. He then moved on to study medicine at the Tufts University School of Medicine. After Pat’s third year, he was awarded a DDCF Clinical Mentorship grant to return to Dr. Yu’s lab for a year, where he currently studies the effects of a group of immunoregulatory receptors found in the adaptive immune system and their role in HIV infection. In addition to enjoying tennis and skiing, he is obsessed with outer space and has aspirations to visit it one day. Pat has returned to Tufts to complete his last year of school.



Amy Shaw

Amy received her BS in Microbiology and Immunology with a minor in Spanish from the University of Miami in 2012. She joined the Xu lab in early summer 2012, where she works as a research technician and as a lab manager in Dr. Yu’s and Dr. Lichterfeld’s labs. She currently works with Dr. Maria Buzon, conducting experiments to better understand the HIV-1 reservoir. When not at work, Amy enjoys going on nature walks with her dog, cooking new recipes, and going to Dave Matthews Band shows.


Selena Vigano

Selena is a postdoctoral fellow at the Ragon institute of MGH, MIT and Harvard. Her research is focused on the investigation of the role of distinct HIV-1-specific CD8 T cells subsets in controlling HIV-1 infection and their contribution to disease progression. She is also involved in a collaborative research project investigating the influence of HDAC inhibitor on the immune system of HIV-1 infected patients. Selena obtained her PhD in Immunology in 2013 from UNIL University and CHUV in Lausanne.