Blog Archives

Click here to visit the Schmidt Lab Website.   Research Summary Our research focuses on the development of adaptive immune responses, protein evolution and the interactions between host and pathogen using a combination of biophysical, biochemical and molecular virology techniques. We are structural biologists who bring mechanistic and quantitative approaches to address fundamental problems in […]

B cells are important immune cells. They produce antibodies against foreign molecules on pathogens, and in this way they protect us against disease.   In our laboratory, we are interested in both the cellular and the molecular events that lead to the activation of B cells. We want to understand how these events affect the […]

The Allen laboratory is primarily investigating the impact that viral sequence diversity has on immune control in the setting of HIV-1 infection. Cellular CD8+ T cell responses (CTL) represent a critical arm of the immune response in the control of HIV-1 infections. The ability of HIV to rapidly evolve and escape from these responses within […]

Shiv Pillai MD, PhD is a Professor of Medicine and Health Sciences and Technology at Harvard Medical School. He is the Program Director of an NIH Funded Autoimmune Center of Excellence at Massachusetts General Hospital and the Director of the Masters in Medical Sciences in Immunology Program at Harvard Medical School.   Dr. Pillai coined […]

Daniel Lingwood was born and raised in Toronto, Canada. He studied physiology at the University of Guelph (BSc) and completed his MSc examining the role of membrane lipids in regulating ion transport ATPases. His subsequent doctoral work at the Max Planck Institute for Molecular Biology and Genetics in Dresden, Germany, helped to define the Lipid Raft […]

Alejandro Balazs received his undergraduate degree at the University of California at Los Angeles and his PhD from Harvard University and is currently an Assistant Professor in medicine at Harvard Medical School.   During his postdoctoral training at the California Institute of Technology, he developed Vectored ImmunoProphylaxis (VIP) as a means of engineering humoral immunity, […]

T cell immune recognition and clearance of pathogen-infected cells relies on the presentation of pathogen-derived peptides by MHC molecules. These peptides come from the degradation of pathogen-derived antigens by the antigen processing machinery of cellular compartments in which the pathogen enters and replicates.  In chronic infections such as HIV or MTb the degradation processes and […]

Galit Alter received her PhD in experimental medicine from McGill University, and is currently a Professor in Medicine at Harvard Medical School. Over the past 8 years her research has focused on understanding the role of the innate immune response to chronic viral infections, including HIV and HCV, with a focus on defining the role […]

The Walker laboratory focuses on mechanisms of immune control in HIV infection, focusing in particular on persons who control HIV infection spontaneously without the need for medication. Through an international collaboration now funded by the Gates Foundation, more than 1500 persons who control HIV infection to less than 2000 RNA Copies/ml without the need for […]

See our full website at: kwonlab.org   The focus of the Kwon lab is the application of new technologies to the study of immune responses against HIV at mucosal surfaces.   Mucosal surfaces represent both the primary site of HIV transmission and the largest reservoir of viral replication. Despite this, the immune response to HIV […]