Date: August 23, 2012 By:
“Mice can tell us a great deal about disease. But they’ve been of limited use in AIDS research because only humans get HIV. Now, researchers have transplanted human bone marrow into mice that lack a functioning immune system. The mice then developed a human immune system, according to Ragon Institute immunologist Todd Allen. He and his colleagues then studied the mice after they were exposed to HIV.”
Their findings, to be published in Cell next month, reveal how the virus manipulates immune system processes to avoid destruction by natural killer (NK) cells, a type of white blood cell that is crucial for fighting viral infections.
The lab of the Ragon Institute faculty member Hernandez Moura Silva, PhD, recently published a review in Science Immunology regarding resident tissue macrophages (RTMs), shedding light on their multifaceted roles in organ health.
After three years off due to the COVID-19 pandemic, the Ragon-MIT course HST.434 returned this January to provide 24 students a once in a lifetime learning experience