Category Archives: research

Ragon Institute Hosts Cellular Immunity Workshop

Feb 02

Ragon Institute Hosts Cellular Immunity Workshop

On January 4th and 5th, 2018, leading researchers in the field of cellular immunology participated in an interactive workshop entitled “Prospects for designing and testing vaccines to elicit cellular immunity against HIV”, hosted by the Ragon Institute of MGH, MIT, and Harvard.   The meeting focused on how cell-mediated immunity can be incorporated into the […]

Read more
New Insights into the Early Immune Response against Viral Infection

Jan 25

New Insights into the Early Immune Response against Viral Infection

  • posted by Ragon Institute
  • in research
  • Comments Off on New Insights into the Early Immune Response against Viral Infection Comments

Vivian Chou | Harvard Medical School In a recent report in Cell, researchers at the Ragon Institute in Cambridge, MA and their collaborators announced a groundbreaking new model of how immunity is initiated in response to viral infections. Achieving broad and long-lasting protection against viruses such as influenza, HIV, and Zika has been a longstanding […]

Read more
Clinical Efficacy Trial of Ragon Institute-Supported HIV Vaccine Underway in Africa

Dec 01

Clinical Efficacy Trial of Ragon Institute-Supported HIV Vaccine Underway in Africa

  • posted by Ragon Institute
  • in research
  • Comments Off on Clinical Efficacy Trial of Ragon Institute-Supported HIV Vaccine Underway in Africa Comments

“Mosaic” vaccine designed to respond to many viral strains, address challenge of genetic diversity. Sue McGreevey | Massachusetts General Hospital A phase 2b clinical trial of a novel preventive HIV vaccine regimen developed by researchers at the Ragon Institute of Massachusetts General Hospital (MGH), MIT and Harvard, Beth Israel Deaconess Medical Center (BIDMC), and partners has […]

Read more
Researchers Develop New Method to Generate Human Antibodies

Jul 25

Researchers Develop New Method to Generate Human Antibodies

  • posted by Ragon Institute
  • in research
  • Comments Off on Researchers Develop New Method to Generate Human Antibodies Comments

An international team of scientists has developed a method to rapidly produce specific human antibodies in the laboratory. The technique, which will be described in a paper to be published July 24, 2017 in The Journal of Experimental Medicine, could speed the production of antibodies to treat a wide range of diseases and facilitate the […]

Read more
Ndhlovu Named HHMI International Research Scholar

Jun 20

Ndhlovu Named HHMI International Research Scholar

Ragon Institute Instructor, Zaza M. Ndhlovu, PhD, is one of forty-one scientists from 16 countries who have been chosen as International Research Scholars through the Howard Hughes Medical Institute (HHMI).   HHMI, along with the Bill & Melinda Gates Foundation, the Wellcome Trust, and the Calouste Gulbenkian Foundation developed this award in order to recognize […]

Read more
Bacterial communities of female genital tract impact HIV infection risk

Jan 10

Bacterial communities of female genital tract impact HIV infection risk

  • posted by Ragon Institute
  • in research
  • Comments Off on Bacterial communities of female genital tract impact HIV infection risk Comments

More diverse vaginal microbiomes in South African women may underlie increased risk   CAMBRIDGE, Mass. – A team of researchers from the Massachusetts General Hospital (MGH) and the Ragon Institute of MGH, MIT and Harvard has found that the most common bacterial community in the genital tract of healthy South African women is associated with […]

Read more
CRISPR Screening Identifies Potential HIV Treatment Targets

Dec 19

CRISPR Screening Identifies Potential HIV Treatment Targets

  • posted by Ragon Institute
  • in research
  • Comments Off on CRISPR Screening Identifies Potential HIV Treatment Targets Comments

Targeting human genes required for viral reproduction but not for T cell survival would avoid inducing treatment resistance   BOSTON – Investigators from the Ragon Institute of MGH, MIT and Harvard and the Broad Institute of MIT and Harvard have used the revolutionary new gene-editing technology CRISPR-Cas9 to identify three promising new targets for treatment […]

Read more
Antibody Function May Help Keep TB Under Control

Sep 22

Antibody Function May Help Keep TB Under Control

A study led by investigators from the Ragon Institute of MGH, MIT and Harvard finds evidence that antibody protection may help control infection with the bacteria that causes tuberculosis (TB).  In their study receiving online publication in Cell, the research team describes finding consistent differences in both the structure and function of antibodies targeting the […]

Read more
From Donation to Research: The Journey of a CD4+ T Cell

Aug 01

From Donation to Research: The Journey of a CD4+ T Cell

  • posted by Ragon Institute
  • in research
  • Comments Off on From Donation to Research: The Journey of a CD4+ T Cell Comments

The Ragon Institute of Mass General Hospital, MIT, and Harvard has a dual mission to contribute to the accelerated discovery of an HIV/AIDS vaccine and subsequently to establish itself as a world leader in the collaborative study of immunology. Thus, the vast majority of studies require the use of peripheral blood cells such as B […]

Read more
New Research Shows Vaccine Protection Against Zika Virus

Jun 28

New Research Shows Vaccine Protection Against Zika Virus

BOSTON – The rapid development of a safe and effective vaccine to prevent the Zika virus (ZIKV) is a global priority, as infection in pregnant women has been shown to lead to fetal microcephaly and other major birth defects. The World Health Organization declared the Zika virus epidemic a global public health emergency on February […]

Read more