Sarah Fortune, MD

Lab Info:

Principal Investigator: Sarah Fortune, MD

Office/Location: HSPH/ 665 Huntington Ave, Boston MA

Phone: (857) 268-7087 or (617) 432-6965


Category: Associate Members

2010 Science and Public Leadership Fellow Sarah Fortune, Professor of Immunology and Infectious Diseases at Harvard T.H. Chan School of Public Health, Harvard Medical School and Brigham and Women’s Hospital, is trying to figure out why the bacterium Mycobacterium tuberculosis is so resistant to treatment. Her team has been studying the disease and the way it responds to various eradication efforts. Despite its virtual eradication in the States, it remains a significant health risk for millions of people worldwide.


Dr. Fortune’s lab focuses on the molecular pathogenesis of M. tuberculosis, combining bacterial genetic approaches with high throughput methodologies to understand the interaction between the bacterium and the infected host. We use techniques such as high density whole genome sequencing and quantitative live cell imaging to define the molecular mechanisms by which M. tuberculosis generates diversity that allows it to survive host selection. Her work seeks to use computational modeling to integrate diverse data sets in order to understand how these processes contribute to the course and burden of human disease.


Watch: Dr. Fortune’s 2011 Pop Tech talk