Category Archives: breaking news

New Research Shows Vaccine Protection Against Zika Virus

BOSTON – The rapid development of a safe and effective vaccine to prevent the Zika virus (ZIKV) is a global priority, as infection in pregnant women has been shown to lead to fetal microcephaly and other major birth defects. The World Health Organization declared the Zika virus epidemic a global public health emergency on February […]

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Study identifies new stem cell-like population where HIV persists in spite of treatment

Recently discovered T memory stem cells may be a long-term viral reservoir, and potential targets for future treatment   Although antiviral therapy against HIV suppresses viral replication and allows infected individuals to live relatively healthy lives for many years, the virus persists in the body, and replication resumes if treatment is interrupted.  Now investigators from […]

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Monoclonal Antibodies Show Promise As Effective HIV Therapy

Oct 30

Monoclonal Antibodies Show Promise As Effective HIV Therapy

BOSTON – A research team led by investigators at Beth Israel Deaconess Medical Center (BIDMC) has demonstrated that a group of recently discovered antibodies may be a highly effective therapy for the treatment of HIV. Published on-line today in the journal Nature, the findings encourage the development of these monoclonal antibodies as a novel therapy […]

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Nanoparticle vaccine offers better protection

Oct 01

Nanoparticle vaccine offers better protection

Ragon Program Leader for Technology Development, Dr. Darrell Irvine discusses a new type of nanoparticle vaccine delivery system which is being researched in his lab.   The nanoparticle system protects the vaccine long enough to generate a strong immune response  in mucosal surfaces far from the vaccination site.   “This is a good example of […]

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Baby HIV ‘Cure’ Promising For African Countries

Mar 04

Baby HIV ‘Cure’ Promising For African Countries

Recent news has reported a Mississippi child who was apparently “cured” of HIV by receiving treatment shortly after birth.  Two years later, the child’s viral loads are undetectable, despite being off treatment for almost a year.   Ragon Institute Principal Investigator Dr. Brian Zanoni speaks to NPR about what could have caused this and what […]

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Ragon Institute Has Moved

Jan 31

Ragon Institute Has Moved

This week the Ragon Institute has completed its move to 400 Technology Square, Cambridge.   This new building space increases Ragon lab and office space significantly, providing a critical step forward in the research and recruitment capabilities of the Institute.  Researchers, staff and collaborators will be housed in three and a half floors of office, […]

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The Indispensables

Sep 01

In 1989, Bruce Walker, an infectious disease specialist at Massachusetts General Hospital, sifted through a tall stack of applications for a technician’s job in his lab. He immediately noticed the application from Alicja Trocha, a recent immigrant from Poland who had joined the anti-Communist Solidarity movement as a student in the 1980s. Trocha had worked […]

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Researchers Find Gene Which Transforms Influenza

Ragon-affiliated researcher, Dr. Abraham Brass and his team find a gene that can transform mild influenza to a life threatening disease.   “A genetic discovery could help explain why flu makes some people seriously ill or kills them, while others seem able to bat it away with little more than a few aches, coughs and […]

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